Mittwoch, 24. Februar 2016

Enviromental fate and pathways-Stability-Phototransformation-Hydrolysis

Enviromental fate and pathways

Stability

Phototransformation in air.001


Administrative data

Purpose flag:
key study
Study result type:
experimental result
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
Chemical kinetics and photochemical data for use in atmospheric studies.
Author:
Sander SP, Friedl RR, Golden DM, Kurylo MJ, Huie RE, Orkin VL, Moortgat GK, Ravishankara AR, Kolb CE, Molina MJ and Finlayson-Pitts BJ
Year:
2003
Bibliographic source:
Evaluation no. 14. NASA Jet Propulsion Laboratory, JPL Publication 02-25. 1st February 2003.

Materials and methods

Principles of method if other than guideline:
No details of the experimental method are provided.
GLP compliance:
no data

Test materials

Identity of test material same as for substance defined in section 1 (if not read-across):
yes
Test material identityopen allclose all

Results and discussion

Degradation rate constant
Reaction with:
OH radicals
Rate constant:
ca. 6.8 cm³ molecule-1 s-1
Any other information on results incl. tables:
Table A7_3_1-1: Equilibrium constants for identified reactions(page 3-2; p 64 of 380 viewed as PDF)
Reaction
A/cm3molecule-1
B/°K
Keq (298K)
f (298K)
g
Notes
Cl + O2 → ClOO
5.7E-25
2500
2.5E-21
2
750
10
ClO + O2 → ClO·O2
2.9E-26
3700
7.2E-21
12
ClO + ClO → Cl2O2
1.27E-27
8744
7.0E-15
1.3
500
13
ClO + OClO → Cl2O3
1.1E-24
5455
9.8E-17
3
300
14
OClO + NO3 → OClONO2
1E-28
9300
3.6E-15
5
1000
15
Where           K(T)/cm3molecule-1 = A exp (B/T) [200 300K]
Table A7_3_1-2: Rate constants for association reactions (termolecular reactions) (from p 2-5; p45 of 380)
Reaction
Low-pressure limit
High-pressure limit
Notes
k0300
n
k300
m
              M
Cl + O2 → ClOO
2.7 ± 1.0 (-33)
1.5 ± 0.5
-
-
F1
                    M
ClO + NO2 → ClONO2
1.8 ± 0.3 (-31)
3.4 ± 0.2
1.5 ± 0.4 (-11)
1.9 ± 0.5
F8
                      M
OClO + NO3 → O2ClONO2
-
-
-
-
F9
                   M
Cl O+ ClO → Cl2O2
1.6 (-32)
4.5
2.0 (-12)
2.4
F10 *
                      M
ClO + OClO → Cl2O3
6.2 ± 1.0 (-32)
4.7 ± 0.6
2.4 ±1.2 (-11)
0 ± 1.0
F11
                  M
OClO + O → ClO3
1.9 ± 0.5 (-31)
1.1 ± 1.0
3.1 ± 0.8 (-11)
0 ± 1.0
F12

Table A7_3_1-3: Rate constants for other reactions (second-order) (from p 1-16; p 139 of 380)
Reaction
A factor  (cm3molecule-1s-1)
E/R
k (298K) (cm3molecule-1s-1)
f (298K)
g
Notes
O + ClO → Cl + O2
3.0E-11
-70
3.8E-11
1.15
70
F1
O + OClO → Cl + O2
2.4E-12
960
1.0E-13
2.0
300
F2
O3 + OClO → products
2.1E-12
4700
3.0E-19
2.5
1000
F7
OH + ClO → Cl + HO2
                  → HCl + O2
7.4E-12
6.0E-13
-270
-230
1.8E-11
1.3E-12
1.4
3.0
100
150
F10
OH + OClO → HOCl + O2
4.5E-13
-800
6.8E-12
2.0
200
F11
HO2 + ClO → HOCl + O2
2.7E-12
-220
5.6E-12
1.3
200
F46
NO + OClO → NO2 + ClO
2.5E-12
600
3.4E-13
2.0
300
F48
Cl + OClO → ClO + ClO
3.4E-11
-160
5.8E-11
1.25
200
F79
Cl + ClOO → Cl2 + O2
2.3E-10
0
2.3E-10
3.0
250
F80
                  → ClO + ClO
1.2E-11
0
1.2E-11
3.0
250
F80
ClO + O3 → ClOO + O2
                → OClO + O2
-
1E-12
-
>4000
1.4E-17
1.0E-18
-
-
-
-
F109
ClO + H2 → products
-1E-12
>4800
1.0E-19
-
-
F110
ClO + NO → NO2 + Cl
6.4E-12
-290
1.7E-11
1.15
100
F111
ClO + NO3 → ClOO + NO2
4.7E-13
0
4.7E-13
1.5
400
F112
ClO + NO2 → products
~1.0E-12
>4300
6.0E-19
-
-
F113
ClO + CO → products
~1.0E-12
>3700
4.0E-18
-
-
F114
ClO + CH4 → products
~1.0E-12
>3700
4.0E-18
-
-
F115
ClO + H2CO → products
~1.0E-12
>2100
1.0E-15
-
-
F116
ClO + CH3O2 → products
3.3E-12
115
2.2E-12
1.5
115
F117
ClO + ClO → Cl2 + O2
                  → ClOO + Cl
                  → OClO + Cl
1.0E-12
3.0E-11
3.5E-13
1590
2450
1370
4.8E-15
8.0E-15
3.5E-15
1.5
1.5
1.5
300
500
300
F118
f(298K) is the uncertainty at 298K

Applicant's summary and conclusion


Phototransformation in air.002



Administrative data

Purpose flag:
supporting study
Study result type:
experimental result
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
Test not undertaken to international guidelines or GLP, but well designed and undertaken under carefully controlled conditions.

Data source

Reference
Reference Type:
publication
Title:
Photodecomposition of chlorine dioxide and sodium chlorite in aqueous solution by irritatin with ultraviolet light.
Author:
Cosson H and Ernst WR
Year:
1994
Bibliographic source:
Industrial Engin. Chem. Res., 33: 1468-1475

Materials and methods

Test guideline
Qualifier:
no guideline followed
Deviations:
not applicable
GLP compliance:
no

Test materials

Identity of test material same as for substance defined in section 1 (if not read-across):
yes
Test material identityopen allclose all
Identifier:
CAS number
Identity:
10049-04-4
Identifier:
EC number
Identity:
233-162-8
Identifier:
IUPAC name
Identity:
chlorous acid
Details on test material:
0.1 M pure chlorine dioxide (7 g/L) in a brown bottle stored in refrigerator.

Study design

Light source:
other: mercury discharge lamp
Light spectrum: wavelength in nm:
>= 253.7 - 300
Details on test conditions:
ubstance concentration: 0.020 - 0.024 mol/l 
Spectrum of substance: Maximum molar extinction (Imax) at 370 nm 
Test medium: Unbuffered deionised water solutions. 
Duration: Until 100 minutes Irradiation conditions: 90% transmission measured down to 200 nm. Maximum of 240 W.

Results and discussion

Test performance - Remarks:
Concentration of substance: 0.020 - 0.024 mol/l Products: Chlorine dioxide residual concentration vs. time. Quantum Yield (number of chlorine dioxide molecules divided by the number of photons adsorbed by the solution): 1.4 at 300 nm and 0.44 at 253.7 nm, both at 25 deg. C.
Quantum yield (for direct photolysis):
1.4

Applicant's summary and conclusion

Hydrolysis.004

Administrative data

Purpose flag:
weight of evidence
Study result type:
experimental result
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
Scientifically justified results, but not following guideline.

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
For the determination of chlorite in water samples Ion Chromatography (IC) is used. Samples were quantified using a calibration curve. The ions are separated in a column and the concentration is measured by conductivity. Positive ions are exchanged to hydrogen ions in a suppressor. The eluent is NaOH with a concentration of 0.01 M. The calibration standards are prepared from a commercial stock solution. For reporting limit 0.01 mg/l chlorite 200 μl sample is injected and for reporting limit 0.005 mg/l 400 μl is used. Every sample is also analyzed with an addition of chlorite standard to confirm the identity of the chlorite peak.

Analytical procedure
Ion chromatograph: Dionex ICS-1000
Autosampler: Dionex AS40
Column: IonPac Dionex AS23, 4X250 mm
Suppressor: Dionex ASRS ULTRA II 4 mm
Eluent: 0.01M NaOH
Injection volume: 200 μl and 400 μl
Flow rate: 1 ml/min
Integration software: Chromeleon vers. 6.5

Performance
For preparing the standards a commercial stock solution was used. New standard was made for every new calibration curve. The calibration series was diluted in MQ-water and in the concentration range of 0.01-5 mg/l and 0.005-5 mg/l chlorite. The samples were filtrated over a 0.45μm filter before analyzing. A standard was analyzed between every sample to check the stability over the calibration curve.
GLP compliance:
no data

Test materials

Identity of test material same as for substance defined in section 1 (if not read-across):
no
Test material identityopen allclose all
Identifier:
CAS number
Identity:
7758-19-2
Identifier:
CAS number
Identity:
10049-04-4
Details on test material:
No data
Radiolabelling:
no
Details on properties of test surrogate or analogue material:
No data

Study design

Analytical monitoring:
no data
Details on sampling:
No data
Buffers:
No data
Details on test conditions:
No data
Number of replicates:
No data
Positive controls:
no data
Negative controls:
no data
Statistical methods:
No data

Results and discussion

Preliminary study:
No data
Test performance:
No data
Transformation products:
no data
Details on hydrolysis and appearance of transformation product(s):
No data
Total recovery of test substance (in %)open allclose all
% Recovery:
ca. 100
Duration:
ca. 4 - < 7 h
% Recovery:
>= 94
Duration:
ca. 7 h
Dissipation half-life of parent compound
Half-life:
ca. 8 h
Remarks (e.g. regression equation, r², DT90):
Study 1
Any other information on results incl. tables:
Table 1: Aerobic abiotic and biotic degradation of chlorite in freshwater.
Test substance
System
Initial concentrations
Method
Degradation
Reference
Sodium chlorite
Natural river water (Mölndalsån) TOC 8 mg/L
0.025, 0.05, 0.075, 0.1 mg/L
Further to addition of the appropriate concentrations of chlorite, samples were taken at 0, 1, 4, 8 and 16 h and immediately analysed using ionic chromatography
A half-life of approximately 8 h was observed at the lowest concentration. Longer half-lives were noted for higher concentrations
EKA Chemicals internal report (in prep)
Sodium chlorite
Natural river water TOC 17 mg/L
0.025, 0.05, 0.075, 0.1 mg/L
Further to addition of the appropriate concentrations of chlorite, samples were taken at 7, 16 and 48 h and immediately analysed using ionic chromatography
The 2 lowest concentrations were below LOQ (0/005 mg/L) within 4 h, 0.075 mg/L was <LOQ within 7 h and 0.1 mg/L was at 0.006 mg/L at this time
EKA Chemicals internal report (in prep)
Sodium chlorite
Natural river water (Dalån) TOC 19 mg/L
0.025, 0.05, 0.075, 0.1 mg/L
Further to addition of the appropriate concentrations of chlorite, samples were taken at 2, 4 and 7 h and immediately analysed using ionic chromatography
All concentrations were below LOQ (0/005 mg/L) in a time period of <7h (the shortest measurement period)
EKA Chemicals internal report (in prep)

Applicant's summary and conclusion




********************************************

Hydrolysis.003

Administrative data

Purpose flag:
key study
Study result type:
experimental result
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
Stability of chlorine dioxide in aqueous solution
Author:
Medir M and Giralt F
Year:
1982
Bibliographic source:
Water Res., 16, 1379-1382

Materials and methods

Principles of method if other than guideline:
Chlorine dioxide was prepared from 20 % sodium chlorite (commercial grade) solution by dropwise addition of 1N sulfuric acid. The generated chlorine dioxide was swept from the solution using nitrogen as carrier, passed through sodium chlorite solution to remove any chlorine formed and dissolved in double distilled water or in an aqueous solution of sodium chloride placed in the reaction vessel.
Reactions were carried out at 25°C in a jacketed pyrex glass reaction vessel of 500 mL protected from light and in the absence of gaseous phase. The pH was maintained constant at 9 by automatic addition of sodium hydroxide from a burette controlled by a pH-stat. 
Experiments were carried out in sodium chloride concentrations of 0, 0.1, 0.4, 0.8 or 2.0 mol/L. Initial concentrations of chlorine dioxide were between 0.002-0.02 mol/L.
The initial concentration of chlorine dioxide was determined by acid-neutral iodometric titration with sodium thiosulfate. Chlorine dioxide consumption was determined by recording the addition of sodium hydroxide. Chlorine dioxide, chlorite and chlorate concentrations were determined by iodometric titration with sodium thiosulfate at different pH values. The chloride concentration was determined by titration with silver nitrate solution using both the Mohr method and the potentiometric method for detection of end point, after flushing the remaining chlorine dioxide out of the solution.
GLP compliance:
no data

Test materials

Identity of test material same as for substance defined in section 1 (if not read-across):
yes
Test material identityopen allclose all
Identifier:
CAS number
Identity:
10049-04-4
Identifier:
EC number
Identity:
233-162-8
Details on test material:
- Analytical purity:

Not reported, however expected to be close to 100 % due to the method of production.
- Other:

Chlorine dioxide was prepared from 20 % sodium chlorite (commercial grade) solution by dropwise addition of 1N sulfuric acid. The generated chlorine dioxide was swept from the solution using nitrogen as carrier, passed through sodium chlorite solution to remove any chlorine formed and dissolved in double distilled water or in an aqueous solution of sodium chloride placed in the reaction vessel.
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Details on test conditions:
Reactions were carried out at 25 °C in a jacketed pyrex glass reaction vessel of 500 mL protected from light and in the absence of gaseous phase. The pH was maintained constant at 9 by automatic addition of sodium hydroxide from a burette controlled by a pH-stat. 
Experiments were carried out in sodium chloride concentrations of 0, 0.1, 0.4, 0.8 or 2.0 mol/L. Initial concentrations of chlorine dioxide were between 0.002-0.02 mol/L.
Duration of test
Duration:
400 min
pH:
9
Temp.:
25 °C
Initial conc. measured:
>= 0.002 - <= 0.02 mol/L
Number of replicates:
One test performed for each set of conditions.
Positive controls:
no data
Negative controls:
no data

Results and discussion

Preliminary study:
Not applicable
Transformation products:
yes
Details on hydrolysis and appearance of transformation product(s):
In the presence of sodium chloride, the degradation products were chlorite and chlorate in a 1:1 ratio.
In the absence of sodium chlorite, the degradation products were chlorate, chlorite, chloride and oxygen in a 5:3:1:0.75 ratio.
Details on results:
In aqueous solution at pH 9 there is a slow initial hydrolysis reaction followed by a more rapid one (Figure 1). The shape of the curve is indicative of an autocatalytic reaction. The length of the induction period for the second reaction is dependent of the concentration of the chlorine dioxide (at 0.02M the induction period is < 100 minutes, whereas at 0.003M the induction period is > 400 minutes). The degradation products are chlorate, chlorite, chloride and oxygen in a 5:3:1:0.75 ratio.
In the presence of sodium chloride there is a slow reaction of a few minutes duration (which is not appreciable in Figure 2) followed by a second faster reaction, which does not present an autocatalytic shape. The degradation products are chlorite and chlorate in a 1:1 ratio.

Applicant's summary and conclusion

Conclusions:
Aqueous solutions of chlorine dioxide are fairly stable at 25°C and pH 9 for an initial period of time before a fast decomposition takes place. The length of the initial stable period decreases with increasing chlorine dioxide concentration and in the presence of inert electrolytes. The reaction products are chlorate, chlorite, chloride and oxygen. Addition of sodium chloride reduces significantly the induction time, but slows down the second reaction and changes the product distribution to equal amounts of chlorite and chlorate.
Validity criteria fulfilled:
not applicable

*********************************

Hydrolysis.002


Administrative data

Purpose flag:
weight of evidence
Study result type:
experimental result
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The chemical model used to understand the disappearance of disinfection residuals (chlorine dioxide, chlorite and chlorate) in ballast water treated with up to 5 mg/L chlorine dioxide is based on analytical data gathered from numerous studies of treated waters from various locations world-wide.
Consider that a defined volume of water previously treated with chlorine dioxide and having a residual concentration of about 1 mg/L chlorine dioxide (e.g., treated ballast) is diluted with an equal volume untreated water. If no additional demand is contained in the dilution water one would expect
to see a 50% reduction in concentration due to the 1:1 dilution … or a concentration of 0.5 mg/L.
GLP compliance:
no

Test materials

Identity of test material same as for substance defined in section 1 (if not read-across):
yes
Test material identityopen allclose all
Identifier:
CAS number
Identity:
10049-04-4
Identifier:
CAS number
Identity:
7758-19-2
Identifier:
CAS number
Identity:
7775-09-9
Details on test material:
- Name of test material (as cited in study report): Chlorine dioxide, chlorite, chlorate
- Molecular formula (if other than submission substance): ClO2, ClO2-, and ClO3-
No other information.
Radiolabelling:
no
Details on properties of test surrogate or analogue material:
no data

Study design

Analytical monitoring:
yes
Details on sampling:
no data
Buffers:
no data
Details on test conditions:
no data
Number of replicates:
no data
Positive controls:
no data
Negative controls:
no data
Statistical methods:
no data

Results and discussion

Preliminary study:
no data
Transformation products:
yes
Identity of transformation productsopen allclose all
No.:
#1
Identifier:
common name
Identity:
Chlorite ion
No.:
#2
Identifier:
common name
Identity:
Chlorate ion
Details on hydrolysis and appearance of transformation product(s):
- Formation and decline of each transformation product during test: ClO2 --> ClO2- + e-
- Pathways for transformation: ClO2 --> ClO2- --> ClO3-
- Other: none
Other kinetic parameters:
no data
Details on results:
 5 mg/L ClO2 is typically undetectable within 24 hours of application…in most applications it is undetectable within 1-2 hours
 ClO2 does not chlorinate, thus chlorinated by-products are not observed
 ClO2 reacts to form primarily chlorite (ClO2-) and chlorate (ClO3-)…the initial chlorate level is typically <10% of the applied dose
 ClO2, ClO2- and ClO3- have shown demand in both the NIOZ and NJ source waters
 ClO2, ClO2- and ClO3- will quickly react (minutes time-scale) with untreated dilution water to lower the residual concentration below measurement detection levels…the worst case from the various studies (NIOZ and shipboard) indicate that 9 dilution volumes are required to lower the concentration of all residual species to undetectable levels within 2 minutes.
 Initial rate data indicate that the reactions of chlorine dioxide and chlorite in untreated waters is fast
 The loss in chlorate upon dilution is believed to involve the enzyme nitrate-reductase (NR)
 The complete reaction of chlorine dioxide and its by-products is believed to result in the formation of chloride ion ClO2 → ClO2- → → Cl-→ ClO3- → → Cl-
Any other information on results incl. tables:
All the figures are presented in attached files.
Figure 1: NJ Ballast Water Chlorine dioxid demand 5.05 mg/L, 24°C
Figure 2: Chlorine dioxide demand NIOZ Low salinity water
Figure 3: Chlorite ion demand study NIOZ 0.98 mg/L, ambient
Figure 4: Chlorate ion demand study NIOZ 1.8 mg/L, ambient
Figure 5: Chlorine dioxide dilution demand NIOZ 1.82 mg/L, ambient
Figure 6: Chlorite dilution demand NIOZ 1 mg/L, ambient
Figure 7: Chlorite dilution demand NJ water 1.4 mg/L, 20°C
Figure 8: Chlorate dilution demand NIOZ 1.57 mg/L, ambient
Figure 9: Chlorate dilution demand NJ water 1.5 mg/L, 20°C

Applicant's summary and conclusion

Conclusions:
The presented data show that any chlorine dioxide residuals that might be present following the treatment of ballast water will quickly be consumed by dilution and demand.
Executive summary:
Chlorine dioxide, chlorite and chlorate show similar demand features when tested in diverse waters… NIOZ (The Netherlands); NJ (East Coast USA). Both waters show an initial fast demand for chlorine dioxide along with a slower continuing loss of chlorite and chlorate ions. Dilution of the treated water with the source water shows demand for chlorine dioxide, chlorite and chlorate beyond what can be accounted for by dilution. This dilution-demand act to further remove any residuals that might be present at the time of ballast release. The initial rate of chlorine dioxide loss appears to be relatively constant however increases are observed for more industrial source waters compared to more pristine source waters. The initial rate of chlorite ion loss appears to be similar to NIOZ and NJ source waters regardless of temperature.
The initial rate of chlorate ion loss in NIOZ water appears to be temperature dependent and is thought to involve the enzymatic reaction of nitrate-reductase.
Validity criteria fulfilled:
yes




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