Genetic toxicity: in vitro.009

Genetic toxicity: in vitro.009

Administrative data

Study result type:

experimental result

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

The study is not performed on the chlorine dioxide itself but on drinking water treated or not with gaseous chlorine or chlorine dioxide.

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

1999

Materials and methods

Results and discussion

Applicant's summary and conclusion

Executive summary:

The authors investigated drinking water from three plants in Northern Moravia with regard to genotoxic effects which are frequently potentiated by the method of chlorine treatment. Water samples, plain and treated, were tested by Ames test and the SOS chromostest. In both short-term tests the genotoxicity of drinking water was confirmed, whereby after desinfection by chlorine treatment the genotoxic potential of water samples increased. On comparison of drinking water treated with gaseous chlorine and chlorine dioxide the latter had more favourable parameters from the genotoxic aspect.